Features which are usually important to only the largest distributors. And the great news is that this list is shrinking all the time! For example:

• While we support a range of costing methods (FIFO, LIFO, Average), we do not provide a choice of costing systems for different types of inventory. (FIFO for stock tab, average for computer products, etc.)
• We do not offer inventory releases by lot. In other words, although Simple Accounting
  can tell you that you have purchased 30 cartons in this lot and 100 in that
  lot, you cannot, currently, specify that you wish to release from a particular lot. You can specify releases from a location, but not a particular lot at that location.
• We do not offer a payroll module, although you should stay tuned as we are considering providing links to other payroll packages if the demand is there.